Introduction: Procalcitonin plasma concentration (PCT) has been suggested as a biomarker for acute infection (usually bacterial). Concentrations increase rapidly within 4-6 hours of infection [1]. However PCT also increases following events such as birth and surgery without any known infection [2, 3]. It is important to understand the time course of PCT following these events […]
A Bokor
- University of Auckland
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Time Course of Procalcitonin – Imputation of Missing Clock Times
January 21, 2022
Authors Abigail Bokor, Jacqueline Hannam, Nick Holford
Affiliations Department of Pharmacology and Clinical Pharmacology, University of Auckland
Presentation type Oral
Presenters Abigail Bokor
Background: Concentrations of endogenous procalcitonin (PCT) increase within hours of infection, and after events such as birth and surgery [1]. Determining the natural history of procalcitonin may help identify abnormal increases indicative of infection. However, in the dataset only the date of observations are recorded without the clock times [2]. If clock times are unavailable, […]