7 February 2005 – 9 February 2005
The 7th Annual Population Analysis WorkShop (PAWS) and Population Approach Group in Australia and New Zealand (PAGANZ) meeting will be held in Brisbane, Queensland, Australia. Both meetings will take place in within the University of Queensland’s St Lucia Campus. http://www.uq.edu.au/maps
Weather at this time of year will be typically warm, with daytime temperatures will be >30C and night time temperatures
rarely drop below 20C. Come and enjoy this great climate!
We look forward to seeing you in sunny Brisbane.
Monday 7 – Wednesday 9 February 2005
University of Queensland, Australia
Last Updated 19 May 2005
Field:
Pharmacometrics, particularly regarding the design, analysis, interpretation and application of pharmacokinetic-pharmacodynamic studies.
PAWS Themes:
Learning Population Analysis and NONMEM from the beginning.
Coding of Pharmacokinetic and Pharmacodynamic Models using NONMEM
Who should attend?
The PAWS and PAGANZ meeting is the Australasian forum for scientists with a research and professional interest in the use of the population approach in pharmacokinetics and pharmacodynamics. A strong focus of this meeting is the application of population modelling and simulation techniques in the experimental, clinical and regulatory settings of drug development.
This meeting is designed for scientists and clinicians working in basic or clinical pharmacology research, pharmaceutical industry, regulatory bodies and postgraduate students. The meeting combines a hands on workshop lead by leaders in the field and a one day scientific meeting giving researchers the opportunity to present and discuss their own work. This is a very informal meeting and in the past has been very productive in helping and guiding researchers in this important area of pharmacology and drug development.
When:
PAWS Monday 7th and Tuesday 8th February 2005
PAGANZ Tuesday 8th and Wednesday 9th February 2005
Poster or Oral Communication Abstract Submission
As part of the PAGANZ scientific meeting researchers will have an opportunity to display research poster and also present a 5 minute overview of their research with a chance for discussion by attending scientists. This has been an informal and most valuable aspect of previous meetings.
Deadline for Abstract Submission: 28th January 2005
Abstract Format: Presenters should submit a 1 A4 page summary of their research with a Title, all authors and affiliations.
Abstracts should be emailed as a Word document attachment to:
Email Subject: PAGANZ 2005 abstract
Registration
Cost: A$215 (including social programme)
Venue
Steele Building
University of Queensland
Brisbane
Queensland, Australia
Accommodation
Please arrange your own accommodation.
Organizing Committee
Carl Kirkpatrick, University of Queensland, Australia
Lena Friberg, University of Queensland, Australia
Bruce Charles, University of Queensland, Australia
Stephen Duffull, University of Queensland, Australia
Nick Holford, University of Auckland, New Zealand
Diane Mould, Projections Research Inc., Pennsylvania, USA
For more information contact
Carl Kirkpatrick
PAWS Workshop
The course will consist of lectures and hands-on exercises at a computer. During the hands-on exercises, tutors will be available for consultation and assistance.
The Beginners Course and the Intermediate Course will be conducted as parallel sessions. Attendance at the Intermediate Course requires experience with the conduct of at least one population approach analysis.
Duration – 1.5 days.
The course will consist of lectures and hands-on exercises at a computer. During the hands-on exercises, tutors will be available for consultation and assistance.
The Beginners Course and the Intermediate Course will be conducted as parallel sessions. Attendance at the Intermediate Course requires experience with the conduct of at least one population approach analysis. Sessions highlighted in yellow indicates computer laboratory tutorial.
Monday 7th of February
| Intermediate Workshop | Beginners Workshop | ||||
| Time | Lecture title | Tutor(s ) – Room | Lecture title | Tutor(s) – | |
| 7:30 | Coffee and registration | Steele building courtyard | Coffee and registration | Steele building courtyard | |
| 8:00 | Introductory lecture on PKPD effect compartment and turnover | Nick Holford
Rm 3-323 |
Introduction to NONMEM I Rm 3 323 | Steve Duffull, Carl – Kirkpatrick – Rm 3-329 |
|
| 10:00 | Morning Tea | Steele building courtyard | Morning Tea | Steele building courtyard | |
| 10:30 | Immediate Drug Effect | Diane Mould
Rm ezone 3 l Level 2, Duhig Building |
Introduction to NONMEM II | Steve Duffull, Carl Kirkpatrick
Rm 3-329 |
|
| 11:30 | Effect compartment Modelling ($PRED & ADVAN4) | Nick Holford Rm ezone 3 l Level 2, Duhig Building |
Introduction to NONMEM III | Steve Duffull, Carl Kirkpatrick
Rm 3-329 |
|
| 12:30 | Lunch | Steele building courtyard | Lunch | Steele building courtyard | |
| 13:30 | Writing $DES in NONMEM | Diane Mould
Rm 3-323 |
Hands on NONMEM I | Steve Duffull, Carl Kirkpatrick – Rm ezone 3 l Level 2, Duhig Building |
|
| 14:30 | Simultaneous vs sequential PK/PD modelling (JC) focusing on Zhang1 Paper | Lena Friberg Rm 3-323 |
Hands on NONMEM II | Steve Duffull, Carl Kirkpatrick ezone 3 l Level 2, Duhig Building |
|
| 15:30 | Afternoon Tea | Steele building courtyard | Afternoon Tea | Steele building courtyard | |
| 16:00 | Coding turnover models | Diane Mould
Rm 3-323 |
Hands on NONMEM III | Steve Duffull, Carl Kirkpatrick ezone 3 l Level 2, Duhig Building |
|
- Simultaneous vs. Sequential Analysis for Population PK/PD Data I: Best-Case Performance. Zhang et al., J PKPD. December 2003, Volume 30, Issue 6 387-404
Tuesday 8th of February
| Intermediate Workshop | Beginners Workshop | |||||
| Time | Lecture title | Presenter/tutor(s) | Lecture title | Presenter/tutor(s) | ||
| 7:30 | Coffee and registration | Steele building courtyard | Coffee and registration | Steele building courtyard | ||
| 8:00 | Effect compartment Modelling (ADVAN6) |
Nick Holford ezone 3 l Level 2, Duhig Building |
Journal Club | Steve Duffull, Carl Kirkpatrick Rm 3-329 |
||
| 9:00 | Turnover models | Diane Mould ezone 3 l Level 2, Duhig Building |
Steve Duffull, Carl Kirkpatrick Rm 3-329 |
|||
| Morning Tea (9:30am) | ||||||
| 10:00 | Morning tea | Steele building courtyard | Project | Steve Duffull, Carl Kirkpatrick ezone 3 l Level 2, Duhig Building |
||
| 10:30 | Review of what has been learnt to date and question session | Nick Holford, Diane Mould, Lena Friberg Rm 3-323 |
Project | Steve Duffull, Carl Kirkpatrick ezone 3 l Level 2, Duhig Building |
||
| 1200 | Lunch | Steele building courtyard | Lunch | Steele building courtyard | ||
| 13:00 | PAGANZ Scientific Meeting | PAGANZ Scientific Meeting | ||||
PAGANZ Scientific Meeting
The PAGANZ meeting will include a symposium highlighting recent advances in the application of the population approach to pharmacokinetics and pharmacodynamics in different clinical settings and in drug development. The symposium speakers will include international and local experts in the field and presents a unique opportunity for Australasian scientists to see the best in action. Two sessions will be dedicated to free communications and discussions providing a forum for researchers to present their work and receive feedback and advice from their peers in an informal setting.
PAWS – POPULATION APPROACH WORKSHOP
PAGANZ Scientific Meeting 2005
Tuesday 8th February 2005
| Time | Lecture title | Presenter/room | Chairperson |
| 13:00 | Annual General Meeting Rm 3-329 | ||
| 14:00 | Oral Presentations | Rm 3-329 | Diane Mould |
| 14:00 | Pharmacokinetic-pharmacodynamic relationships of ralitrexed in cancer patients | Elaine Blair | |
| 14:20 | A population pharmacokinetic-pharmacodynamic model to investigate the effect of herbal medicines on warfarin response in healthy | XueminJiang
|
|
| 14:40 | A pharmacokinetic study of docetaxel in Asian breast cancer patients: relating exposure to primary tumor reduction | Lai San Tham | |
| 15:00 | Assessment of predictive performance of pharmacokinetic models based on rich plasma and urine data | Juergen Bulitta | |
| 15:30 | Afternoon Tea – Steele building courtyard | ||
| 16:00 | Poster Orals – Steele building courtyard | Steele building courtyard |
Nick Holford |
| Pharmacokinetics of Liposomal Amphotericin B in Children with Persistent Fever and Neutropenia | Renee Ying Hong | ||
| 18:00 | Social Evening – Conference Dinner Customs House, Inner City. Catch Citycat at 6:06pm, University of Queensland, City-Cat terminal (see map). |
||
Wednesday 9th February 2005
| Time | Lecture title | Presenter | Chairperson |
| 8:30 | Coffee and registration – Steele building courtyard | ||
| 9:00 | Oral Presentations – UQ Session – | Room 3-329 | Andrew McLachlan |
| 9:00 | Pharmacokinetic-pharmacodynamic modelling of QT-prolongation after deliberate self-poisoning with citalopram | Lena Friberg | |
| 9:30 | Quantification of lean body weight | Sarayut Janmahasatian | |
| 9:50 | Evaluation of Cystatin C as a diagnostic test for altered renal function – A meta-analysis approach | Juliana Roos | |
| 10:10 | TBA | Andrea Lennie | |
| 10:30 | Coffee and Poster session – Steele building courtyard | ||
| 11:00 | Symposium – Professor Yusuke Tanigawara | Rm 3-329 | Nick Holford |
| 12:00 | Lunch – Steele building courtyard | ||
| 13:00 | Tutorial – Covariate models | Rm 3-329 | Steve Duffull |
| 15:00 | Afternoon Tea and Conference close | ||