PAGANZ Scientific Program 7th – 8th February
Tuesday 7th February 2017 |
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| Time | Session Topic | Speaker |
| 13:30 | Welcome to PAGANZ Scientific Meeting | |
| 13:35 | ISoP Lecture: PK/PD Modeling and Simulation to Streamline Drug Development on Earth and in Space | Hartmut Derendorf |
| 14:30 | Tea + Posters | |
| Free Papers – South Australian Focus | Chair: David Foster | |
| 15:00 | Population in vitro-in vivo correlation model linking gastrointestinal transit time, pH with the in vivo disposition kinetics of itraconazole | Ahmad Abuhelwa |
| 15:15 | Population Pharmacokinetic Model of Doxycycline Plasma Concentrations – Pooled Study Data | Ash Hopkins |
| 15:30 | Guest commentary | Stuart Mudge |
| 15:45 | Comparison of Non-Compartmental and Mixed Effect Modelling Methods for Establishing Bioequivalence for the Case of Two Compartment Kinetics and Censored Concentrations | Jim Hughes |
| 16:00 | Annual General Meeting | All participants |
| 19:00 | Social evening: Adelaide Rowing Club | |
Wednesday 8th February 2017 |
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| Time | Session Topic | Speaker |
| 8:30 | Coffee | |
| Free Papers – 1 | Chair: Cornelia Landersdorfer | |
| 9:00 | Performance of estimation methods in modelling the kinetics of respiratory virus infection | Kashyap Patel |
| 9:15 | Understanding the sensitivity of international normalized ratio (INR) to variations in clotting factor levels | Qing Xi Ooi |
| 9:30 | Internal Deterministic Identifiability of PK and PKPD Models | Vijay Kumar Siripuram |
| 9:45 | Identifiability analysis of empirical models used for quantifying “biased” ligands | Xiao Zhu |
| 10:00 | Tea + Posters | |
| Free Papers – 2 | Chair: Richard Upton | |
| 10:30 | Mechanism-based PK/PD modelling approach to optimise combination dosage regimens against multidrug-resistant clinical isolates of Pseudomonas aeruginosa and in-vivo evaluation in a murine thigh infection model | Rajbharan Yadav |
| 10:45 | Systems Pharmacology – Application to GAVamycin | Nick Holford |
| 11:00 | Pharmacometric modelling of deuterium exposure in breastfeeding mother-infant pairs for the determination of exclusive breastfeeding practice | Zheng Liu |
| 11:15 | Population pharmacokinetic and pharmacodynamic properties of OZ439 in healthy volunteers and patients with falciparum and vivax malaria | Piyanan Assawasuwannakit |
| 11:30 | Solutions for nonlinear ordinary differential equations in pharmacokinetic-pharmacodynamic systems | Chihiro Hasegawa |
| 11:45 | Influence of study design on choice of the allometric exponent | Jaydeep Sinha |
| 12:00 | Student lunchtime careers session | Cornelia Landersdorfer, Kashyap Patel, David McDougall |
| 12:00 | Lunch | Sponsored by Model Answers |
| Free Papers – 3 | Chair: Carl Kirkpatrick | |
| 13:00 | Infliximab maintenance dosing in inflammatory bowel disease: an example for in silico assessment of adaptive dosing strategies | Jessica Wojciechowski |
| 13:15 | NextDose – A web based dosing tool – Development version 2017 | Nick Holford |
| 13:30 | Assessing the predictive performance of an interactive application to dose adjust voriconazole | David McDougall |
| 13:45 | Improving gentamicin dosing in paediatric oncology patients | Carolina Llanos-Paez |
| 14:00 | ||
| 14:15 | ||
| 14:30 | Tea + Posters | |
| 15:00 | Nick Holford Prize, Closing remarks | Nick Holford |
Poster Presentations
Title: Development of an Interactive Tool to Explore Doses & Sample for Paediatric Trials.
Presenter: David McDougall / Michael Cheng