Program

Tues 13th Feb 2007

Intermediate Workshop

Time

Session Topic

Tutors

8:00

Registration + Coffee

 

8:30

Introduction to Monolix (Hands on)

France Mentre / Marc Lavielle

10:00

Tea Break

 

10:30

Monolix

France Mentre / Marc Lavielle

12:00

Lunch

 

13:00

Monolix (hands on)

France Mentre / Marc Lavielle

15:00

Tea Break

 

15:30

Monolix

France Mentre / Marc Lavielle

17:30

Home

 

 

Wed 14th Feb 2007

Intermediate Workshop

Time

Session Topic

Tutors

8:00

Coffee

8:30

Time-to-event

Nick Holford

10:00

Tea break

10:30

Time-to-event (hands on)

Nick Holford

12:00

Lunch

 

Beginners Workshop:

 Tues 13th Feb 2007

Beginners Workshop

Time

Session Topic

Tutors

8:00

Registration + coffee

8:30

Introduction to NONMEM I

Carl Kirkpatrick, Bruce Green

10:00

Tea break

10:30

Hands on NONMEM I

Carl Kirkpatrick, Bruce Green, Bruce Charles

12:00

Lunch

13:00

Introduction to NONMEM II

Carl Kirkpatrick, Bruce Green

15:00

Tea Break

15:30

Hands on NONMEM II

Carl Kirkpatrick, Bruce Green, Bruce Charles

17:30

Home

   

Wed 14th Feb 2007

Beginners Workshop

Time

Session Topic

Tutors

8:00

Coffee

8:30

Project (Hands-on)

Carl Kirkpatrick, Bruce Green

10:00

Tea Break

10:30

Journal Club / Consultation

Carl Kirkpatrick, Bruce Green

12:00

Lunch

 

PAGANZ:

Wed 14th Feb 2007

PAGANZ

Time

Session Topic

  

Speaker

 Chairperson

13:00

Oral communications:

1. Different ways of incorporating data below the quantification limit in datasets for parameter estimation.

2. Optimal designs of studying bioimpedance – design for nonlinear mixed-effects models.

3. Population pharmacokinetics of amikacin in very premature Malaysian neonates.

4. Population pharmacokinetics of oral and intravenous caffeine in extremely premature neonates

5. Preclinical population PK/PD of TGF beta RI kinase inhibitor for cancer.

S. Hennig

J.M. McGree

Y.L. Lo

B.G. Charles

S. Glatt

Carl Kirkpatrick

 

 

 

 

 

 

 

 

15:00

Tea Break

 

15:30

Role of Pharmacometrics in Regulatory Decision Making

Cynthia Sung

Nick Holford

16:00

 PK/PD model of gemcitabine in Asian non-small cell lung cancer

Lai-San Tham

Nick Holford

16:30

 Modelling of PET imaging data of an antipsychotic drug

In-Jin Jang

Nick Holford

17:00

Annual general meeting followed by social evening

   
 

Thurs 15th Feb 2007

PAGANZ

Time

Session Topic

Speaker

Chairperson 

8:00

Coffee

8:30

Oral Communications II

1. Development of a sufficient design for parameter estimation of fluconazole population.

2. Comparison of different diagnostic criteria to evaluate nonlinear mixed-effects models.

3. Normalized prediction distribution errors for the evaluation of nonlinear mixed-models.

J.F. Roos

C. E. Staatz

F. mentre

Steve Duffull

9:30

Maximum likelihood estimation in nonlinear mized effects models with the SAEM algorithm

Marc Lavielle

Steve Duffull

10:15

Tea Break + Poster Session

10:45

Diagnosing Diagnostics

Mats Karlsson

Bruce Charles

11:30

Size Does Matter

Bruce Green

Bruce Charles

12:15

Lunch

13:15

Sense and Sensitivity

Leon Aarons

Bruce Green

14:00

Tea Break + Poster

14:30

Oncology application of NONMEM – PDX

Diane Mould

Bruce Green

15:15

Oral Communications III

1. Population pharmacokinetic analysis of morphine in opioid dependent and control subjects.

2. Pharmacokinetics of L-arginine after intravenous infusion on adults with moderately severe malaria.

3. Pharmacokinetics of quetiapine in overdose

G.A. Morrish

T.W. Yeo

G.K. Isbister

Nick Holford

16:40

Home

 

Invited Speakers

 

Bruce Green

Lecturer

School of Pharmacy

University of Queensland

Australia

 

Mats Karlsson

Professor of Pharmacometrics

Division of Pharmacokinetics and Drug Therapy

Department of Pharmaceutical Biosciences

Faculty of Pharmacy

Uppsala University, Sweden

 

France Mentre

Professor

INSERM U738, Dpt of Epidemiology, Biostatistics and Clinical Research

Hospital Bichat

University Paris 7

France

 

Marc Lavielle

Professor of Mathematics

IUT, University Paris-Sud

France

 

Leon Aarons

Professor

University of Manchester

United Kindom

 

In-Jin Jang

Professor of Clinical Pharmacology

Seoul National University

Seoul

Korea

 

Diane R Mould

President

Projections Research Inc.

Phoenixville, PA

U.S.A.

 

Cynthia Sung

President

Rainbow Pharma Consulting

Singapore

 

Lai-San Tham

PK/PD Scientist

Lilly-NUS Centre for Clinical Pharmacology

Singapore