Tues 13th Feb 2007 |
Intermediate Workshop |
|
Time |
Session Topic |
Tutors |
8:00 |
Registration + Coffee |
|
8:30 |
Introduction to Monolix (Hands on) |
France Mentre / Marc Lavielle |
10:00 |
Tea Break |
|
10:30 |
Monolix |
France Mentre / Marc Lavielle |
12:00 |
Lunch |
|
13:00 |
Monolix (hands on) |
France Mentre / Marc Lavielle |
15:00 |
Tea Break |
|
15:30 |
Monolix |
France Mentre / Marc Lavielle |
17:30 |
Home |
Wed 14th Feb 2007 |
Intermediate Workshop |
|
Time |
Session Topic |
Tutors |
8:00 |
Coffee |
|
8:30 |
Time-to-event |
Nick Holford |
10:00 |
Tea break |
|
10:30 |
Time-to-event (hands on) |
Nick Holford |
12:00 |
Lunch |
|
Beginners Workshop:
Tues 13th Feb 2007 |
Beginners Workshop |
|
Time |
Session Topic |
Tutors |
8:00 |
Registration + coffee |
|
8:30 |
Introduction to NONMEM I |
Carl Kirkpatrick, Bruce Green |
10:00 |
Tea break |
|
10:30 |
Hands on NONMEM I |
Carl Kirkpatrick, Bruce Green, Bruce Charles |
12:00 |
Lunch |
|
13:00 |
Introduction to NONMEM II |
Carl Kirkpatrick, Bruce Green |
15:00 |
Tea Break |
|
15:30 |
Hands on NONMEM II |
Carl Kirkpatrick, Bruce Green, Bruce Charles |
17:30 |
Home |
|
|
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Wed 14th Feb 2007 |
Beginners Workshop |
|
Time |
Session Topic |
Tutors |
8:00 |
Coffee |
|
8:30 |
Project (Hands-on) |
Carl Kirkpatrick, Bruce Green |
10:00 |
Tea Break |
|
10:30 |
Journal Club / Consultation |
Carl Kirkpatrick, Bruce Green |
12:00 |
Lunch |
|
PAGANZ:
Wed 14th Feb 2007 |
PAGANZ |
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Time |
Session Topic |
Speaker |
Chairperson | ||
13:00 |
Oral communications: 1. Different ways of incorporating data below the quantification limit in datasets for parameter estimation. 2. Optimal designs of studying bioimpedance – design for nonlinear mixed-effects models. 3. Population pharmacokinetics of amikacin in very premature Malaysian neonates. 4. Population pharmacokinetics of oral and intravenous caffeine in extremely premature neonates 5. Preclinical population PK/PD of TGF beta RI kinase inhibitor for cancer. |
S. Hennig
J.M. McGree
Y.L. Lo
B.G. Charles
S. Glatt
|
Carl Kirkpatrick
|
||
15:00 |
Tea Break |
|
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15:30 |
Role of Pharmacometrics in Regulatory Decision Making |
Cynthia Sung |
Nick Holford | ||
16:00 |
PK/PD model of gemcitabine in Asian non-small cell lung cancer |
Lai-San Tham |
Nick Holford | ||
16:30 |
Modelling of PET imaging data of an antipsychotic drug |
In-Jin Jang |
Nick Holford | ||
17:00 |
Annual general meeting followed by social evening |
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Thurs 15th Feb 2007 |
PAGANZ |
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Time |
Session Topic |
Speaker |
Chairperson |
||
8:00 |
Coffee |
|
|
||
8:30 |
Oral Communications II 1. Development of a sufficient design for parameter estimation of fluconazole population. 2. Comparison of different diagnostic criteria to evaluate nonlinear mixed-effects models. 3. Normalized prediction distribution errors for the evaluation of nonlinear mixed-models. |
J.F. Roos
C. E. Staatz
F. mentre
|
Steve Duffull
|
||
9:30 |
Maximum likelihood estimation in nonlinear mized effects models with the SAEM algorithm |
Marc Lavielle
|
Steve Duffull
|
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10:15 |
Tea Break + Poster Session |
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|
||
10:45 |
Diagnosing Diagnostics |
Mats Karlsson |
Bruce Charles |
||
11:30 |
Size Does Matter |
Bruce Green |
Bruce Charles |
||
12:15 |
Lunch |
|
|
||
13:15 |
Sense and Sensitivity |
Leon Aarons |
Bruce Green |
||
14:00 |
Tea Break + Poster |
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|
||
14:30 |
Oncology application of NONMEM – PDX |
Diane Mould |
Bruce Green |
||
15:15 |
Oral Communications III 1. Population pharmacokinetic analysis of morphine in opioid dependent and control subjects. 2. Pharmacokinetics of L-arginine after intravenous infusion on adults with moderately severe malaria. 3. Pharmacokinetics of quetiapine in overdose |
G.A. Morrish
T.W. Yeo
G.K. Isbister |
Nick Holford
|
||
16:40 |
Home |
|
|
Invited Speakers
Bruce Green
Lecturer
School of Pharmacy
University of Queensland
Australia
Mats Karlsson
Professor of Pharmacometrics
Division of Pharmacokinetics and Drug Therapy
Department of Pharmaceutical Biosciences
Faculty of Pharmacy
Uppsala University, Sweden
France Mentre
Professor
INSERM U738, Dpt of Epidemiology, Biostatistics and Clinical Research
Hospital Bichat
University Paris 7
France
Marc Lavielle
Professor of Mathematics
IUT, University Paris-Sud
France
Leon Aarons
Professor
University of Manchester
United Kindom
In-Jin Jang
Professor of Clinical Pharmacology
Seoul National University
Seoul
Korea
Diane R Mould
President
Projections Research Inc.
Phoenixville, PA
U.S.A.
Cynthia Sung
President
Rainbow Pharma Consulting
Singapore
Lai-San Tham
PK/PD Scientist
Lilly-NUS Centre for Clinical Pharmacology
Singapore