The Population Analysis Workshops (PAWs) and the PAGANZ Scientific Program will be held at City West campus, University of South Australia (UniSA), Adelaide, South Australia.
Initial registration will be in the Sir George Kingston Building (GK) City West Campus GK2-15, with the Beginners and Intermediate PAWS in separate parallel sessions. Please see below specific PAWS rooms.
The PAGANZ scientific meeting will be held in the Bradley Forum, of the Hawke Building (H) of the UniSA City West campus.
A detailed map of the UniSA City West Campus is available online here.
Please note that this year we will be running both PAWS as Bring Your Own Device (BYOD)
You will require your own working installation of NONMEM. Meeting attendees will be sent an email containing a link to all PAWS material, including access to NONMEM installation files and a temporary license associated with the meeting.
Intermediate PAWS attendees will also require R Studio an R installation, which is available through most Universities and is free / discounted for researchers. Specific information about the R installation and libraries is provided in the PAWS material. Please ensure that you read this carefully and check the functionality.
Social Events
| Monday 30th January, 2023 | |
| 1830 | Student Social function: The Wellington Hotel, 36 Wellington Square, North Adelaide. Look out for an email from Hailemichael Hishe and Laila Nassar for details! |
| Tuesday 31st January, 2023 | |
| 1800 | PAGANZ Dinner: Majestic Roof Garden Hotel, 55 Frome Street. |
Population Analysis Workshops (PAWs)
Beginners PAWs
Coordinator: Jacqueline Hannam (University of Auckland) and James Morse (University of Auckland)
Monday 30th January, 2023
| 0800 | Registration and coffee | Sir George Kingston Building (GK) City West Campus GK2-15 |
| 0830 | Introduction to population methods | Sir George Kingston Building (GK) City West Campus GK2-16 |
| 1000 | Morning tea | |
| 1030 | Hands on with NONMEM I: Residual variance models | |
| 1200 | Lunch | |
| 1300 | Building structural models | |
| 1500 | Afternoon tea | |
| 1530 | Building covariate models | |
| 1700 | Close |
Tuesday 31st January, 2023
| 0800 | Registration and coffee | Sir George Kingston Building (GK) City West Campus GK2-15 |
| 0830 | Hands on with NONMEM II: Covariate models | Sir George Kingston Building (GK) City West Campus GK2-16 |
| 1000 | Morning tea | |
| 1030 | Critical appraisal and discussion | |
| 1200 | Lunch |
Intermediate PAWs
Monday 30th January, 2023
Pharmacoeconomics – 1 day
Coordinators: Thomas Lung (The George Institute for Global Health / University of Sydney), Tracey Laba (University of South Australia) and David Foster (University of South Australia).
For this workshop there will be a mixture of theory and hands on throughout the day using “R”.
Specific information about the R installation and libraries is provided in the PAWS material. Please ensure that you read this carefully and check the functionality.
| 0800 | Registration and coffee | Sir George Kingston Building (GK) City West Campus GK2-15 |
| 0830 | Introduction to health economic models | Sir George Kingston Building (GK) City West Campus GK2-12 |
| 1000 | Morning tea | |
| 1030 | Health economic modelling I | |
| 1200 | Lunch | |
| 1300 | Health economic modelling II | |
| 1500 | Afternoon tea | |
| 1530 | PK-PD integration to health economics | |
| 1700 | Close |
Tuesday 31st January, 2023
An introduction to CAR-T Population kinetic analyses – 1/2 day
Coordinators: Mirjam Trame (Certara) and Stephen Duffull (Certara)
For this workshop there will be a mixture of theory and hands on throughout the day using NONMEM and your favourite data presentation/visualisation platform for NONMEM outputs.
| 0800 | Registration and coffee | Sir George Kingston Building (GK) City West Campus GK2-15 |
| 0830 | Using Clin Pharm and PMX to Accelerate Cell Therapeutics Development: A Patient’s CAR-T Journey | Sir George Kingston Building (GK) City West Campus GK2-12 |
| 1000 | Morning tea | |
| 1030 | Introduction to CAR-T cell data, data model and model exploration | |
| 1200 | Lunch |
PAGANZ Annual Scientific Meeting
Bradley Forum, Hawke Building (H) City West campus
Tuesday 31st January, 2023
| 1330 | Welcome to the PAGANZ Scientific meeting | David Foster |
| Free oral presentations 1 | Chair: Hailemichael Hishe | |
| 1340 | VPs, QSPs, Ensembles and Education | Stephen Duffull |
| 1415 | New Insights into the Pharmacokinetics of Gentamicin, Amikacin and Vancomycin – from Neonates to Adults | Nick Holford |
| 1435 | Semi-mechanistic modelling of ceftolozane/tazobactam plus tobramycin against planktonic and biofilm bacteria of hypermutable Pseudomonas aeruginosa epidemic strains | Cornelia Landersdorfer |
| 1455 | Tea + Posters | |
| Free oral presentations 2 | Chair: James Morse | |
| 1530 | A Complete Bayesian Workflow in Pumas | Mohamed Tarek |
| 1550 | Preliminary development of a semi physiologically-based pharmacokinetic model for rocuronium | David Foster |
| 1610 | Session ends | |
| 1630 | Annual General Meeting | Jaqueline Hannam |
| 1800 | PAGANZ Dinner: Majestic Roof Garden Hotel, 55 Frome Street |
Wednesday 1st February, 2023
| 0800 | Registration and coffee | |
| 0830 | Welcome | David Foster |
| 0835 | ISoP Lecture “Quantitative systems pharmacology and pharmacometrics in drug development: one, the other or both?” | Piet van der Graaf Senior Vice President, Quantitative Systems Pharmacology Professor of Systems Pharmacology, Canterbury Innovation Centre, Certara. |
| Free oral presentations 3 – Students 1 | Chair: Shaun Kumar | |
| 0930 | Population pharmacokinetics of milrinone in premature neonates to adolescents | Conor O’Hanlon |
| 0950 | The impact of birth on propofol clearance maturation | James Morse |
| 1010 | Tea + Posters | |
| Free oral presentations 4 – Students 2 | Chair: Cornelia Landersdorfer | |
| 1030 | Time Course of Procalcitonin Concentration Following Birth and Surgery | Abigail Bokor |
| 1050 | Mixed-effect meta-analysis of published NCA data for Cannabidiol | Sadikalmahdi Abdella |
| 1110 | A consistent nomenclature for describing pharmacokinetics and dialyser performance | Laila Nassar |
| 1130 | Pharmacodynamic modelling approaches in the setting of suboptimal drug adherence | Hailemichael Hishe |
| 1150 | Favipiravir pharmacokinetics in infants and young children with chronic RNA viral infections | Iek Cheng |
| 1210 | Session ends | |
| 1215 | Student prize presentations and meeting close | Jacqueline Hannam |
| 1230 | Lunch |