Social Events
| Wednesday 6 Feb 2019 | |
| 1700-1900 h | Welcome reception
Galbraith’s Ale House2 Mt Eden Road, Grafton, Auckland |
| Friday 8 Feb 2019 | |
| 1700 h | PAGANZ Dinner
Brothers Brewery
|
PAWS – Beginner workshop
Thursday 7 Feb 2019
| 0800-0830 h | Registration and coffee | Atrium |
| 0830-1000 h | Introduction to population methods | Seminar room 505-003 |
| 1000-1030 h | Morning tea | Atrium |
| 1030-1200 h | Hands on with NONMEM: Residual variance models | Computer lab 503-124 |
| 1200-1300 h | Lunch | Atrium |
| 1300-1500 h | Building Structural Models | Seminar room 505-003 |
| 1500-1530 h | Afternoon tea | Atrium |
| 1530-1700 h | Building Covariate Models | Computer lab 503-124 |
| 1700-1930 h | Cetara Student and Early Careers Night |
Seminar room 503-020 |
Friday 8 Feb 2019
| 0800-0830 h | Registration and coffee | Atrium |
| 0830-1000 h | Hands on with NONMEM II: Covariate models | Computer lab 503-124 |
| 1000-1030 h | Morning tea | Atrium |
| 1030-1200 h | Critical Appraisal and Discussion | Seminar room 505-003 |
| 1200-1300 h | Lunch | Atrium |
End of PAWS program, PAGANZ program commences
PAWS – Intermediate workshop
Thursday 7 Feb 2019
| 0800-0830 h | Registration and coffee | Atrium |
| 0830-1000 h | Part I: TMDD Model and Equations | Computer lab 503‐124 |
| 1000-1030 h | Morning tea | Atrium |
| 1030-1200 h | Part II: TMDD Model Approximations: Derivations, Selection and Applications | Seminar room 505‐003 |
| 1200-1300 h | Lunch | Atrium |
| 1300-1500 h | Part III: Applications to Drug Development of Biologics | Computer lab 503‐124 |
| 1500-1530 h | Afternoon tea | Atrium |
| 1530-1700 h | Part IV: Case Studies | Seminar room 505‐003 |
| 1700-1930 h | Cetara Student and Early Careers Night |
Seminar room 503-020 |
Friday 8 Feb 2019
| 0800-0830 h | Registration and coffee | Atrium |
| 0830-1000 h | Introduction to model definition using CellML and OpenCore | Seminar room 505-003 |
| 1000-1030 h | Morning tea | Atrium |
| 1030-1200 h | Hands on with CellML and OpenCore | Computer lab 503-124 |
| 1200-1300 h | Lunch | Atrium |
End of PAWS program, PAGANZ program commences
PAGANZ Annual Scientific Meeting
Lecture Hall 505-007
Friday 8 Feb 2019
| Session: ISoP Lectureship |
||
| 1330-1335 h | Welcome | Jacqueline Hannam |
| 1335-1415 h | Twenty Five Years of TMDD Development: History, Current State, and Future Directions | Katya Gibiansky Leonid Gibiansky |
| Session: Free oral presentations 1 Chair: Jacqueline Hannam |
||
| 1415-1430 h | A mathematical model for warfarin reversal using vitamin K | Anna Cao |
| 1430-1445 h | Quantifying the Dose-Response of Unfractionated Heparin Using a System Pharmacology Model of Coagulation | Abdallah Derbalah |
| 1445-1500 h | The Influence of Genotype on Warfarin Dose Predictions | Guangda Ma |
| 1500-1530 h | Afternoon tea | |
| Session: Free oral presentations 2 Chair: Janet Wade |
||
| 1530-1545 h | A review of current infusion regimens of propofol in neonates and infants | James Morse |
| 1545-1600 h | A Population Pharmacokinetic Model of Phenobarbitone in Neonates to Determine Oral Bioavailability and Facilitate Individualised Dosing | Angela Williams |
| 1600-1615 h | A Population Pharmacokinetic Study of Caffeine Citrate in Chinese Premature Neonates | Xiaoyan Yang |
| 1615-1630 h | A Population Pharmacodynamic Study of Apnea of Prematurity and the Effect of Caffeine Citrate in Chinese Premature Neonates | Nick Holford |
| 1630-1645 h | Modelling of delivery kinetics of gentamicin administered through umbilical long lines | Gianna Salis |
| 1645-1700 h | Pharmacometric modelling of deuterium exposure in breastfeeding mother-infant pairs for the determination of exclusive breastfeeding practice | Zheng Liu |
| 1700-1800 h | PAGANZ Annual General Meeting | |
Saturday 9 Feb 2019
| 0800-0830 h | Registration and coffee, foyer | |
| Session: 20 years of PAGANZ Chair: Dan Wright |
||
| 0830-0845 h | Twenty years of PAGANZ | Nick Holford |
| 0845-0900 h | Paracetamol over twenty years | Brian Anderson |
| 0900-0915 h | Combining PK and PD data; it was twenty years ago today…. (apologies to Sgt. Pepper) | Janet Wade |
| 0915-0930 h | TBA | Mats Karlsson |
| 0930-0945 h | From the First to the NextDose: My journey through twenty years of PAGANZ | Sam Holford |
| 0945-1000 h | Future work in Auckland: procalcitonin in healthy & infected neonates to inform PKPD disease progression modelling | Jacqueline Hannam |
| 1000-1030 h | Morning tea | |
| Session: Free oral presentations 3 Chair: Stefanie Hennig |
||
| 1030-1045 h | Predictive performance of a Bayesian forecasting software for tacrolimus in adult heart transplant | Ranita Kirubakaran |
| 1045-1100 h | A quantitative systems pharmacology model for glutathione depletion during paracetamol overdose | Jingyun Li |
| 1100-1115 h | An ePKPD model for sodium nitroprusside in adolescents | Salma Bahnasawy |
| 1115-1130 h | Implementation of an approximate input forcing function for modelling single tissues in the Open Pharmacology Suite | Jim H. Hughes |
| 1130-1145 h | Investigating the pharmacokinetics of snake venom – a cocktail of toxins | Suchaya Sanhajariya |
| 1145-1200 h | An extension of Janmahasatian’s fat-free mass model to incorporate differences due to ethnicity | Jaydeep Sinha |
| 1200-1215 h | Evaluation of the fingerprint profiles of the cannabinoid-1 receptor signalling via a kinetic modelling approach | Xiao Zhu |
| 1215-1230 h | Evaluation of study designs to test the intact nephron hypothesis | Sudeep Pradhan |
| 1230-1330 h | Lunch | |
| Session: Free oral presentations 4 Chair: Carl Kirkpatrick |
||
| 1330-1345 h | Student prize presentations | Nick Holford |
| 1345-1400 h | Extrapolation of acetaminophen PK models from adults to paediatricians | Harvey Ho |
| 1400-1415 h | How many NMLE articles are published in higher Impact Factor clinical journals? | Stefanie Hennig |
| 1415-1430 h | Analyzing endpoints with many ordered categories: theory and applications | Chuanpu Hu |
| 1400-1445 h | Dose banding- weighing up benefits vs risks | Stephen Duffull |
| 1445-1500 h | Meeting Closes | |
End of PAGANZ program