31 January 2000 – 2 February 2000
MONDAY, January 31
PAGANZ (I) Room 309, Steele Building, School of Pharmacy, University of Queensland, St Lucia.
08:30 – 08:45
Welcome and introductions (Bruce Charles)
08:45 – 09:15
Background, rationale for population approaches; development and current status of NONMEM (Nick Holford)
9:15 – 09:30
Discussion and questions
09:30 – 10:00
Applications: Covariate models (Nick Holford)
10:00 – 10:30
Discussion and questions
10:30 – 11:00
Morning tea
11:00 – 12:15
Prof Roger Jelliffe, USC Laboratory of Applied Pharmacokinetics, California, USA
Nonparametric Population Models – Strengths and Weaknesses and Contribution to Optimal Dosage Requirements
12:15 – 13:00
Discussion and questions
13:00 – 14:00
Lunch (UQ Staff Club)
PAWS (I) Computer Laboratory, UQ Biological Sciences Library (Ground floor)
14:00 – 17:00 (Afternoon Tea 15:30)
Development of a population model from first principles using a guided, hands-on approach
17:00 – 18:00
Drinks (UQ Staff Club)
TUESDAY, February 1
PAWS (II) Computer Laboratory, Biological Sciences Library
09:00 – 12:00 (Morning Tea 10:30)
Case study in population modelling. Data provided to users who will develop population model(s)
12:00 – 12:30
Discussion of case study
12:30 – 13:30
Lunch (UQ Staff Club)
PAGANZ (II) Room 309, Steele Building, School of Pharmacy
13:30 – 15:00
Open discussion – Hot topics, troubleshooting, controversies
15:00 – 15:30
Afternoon tea
15:30 – 17:30
Individual oral presentations: 10-15 min + 5-10 min discussion
17:30 – 18:30
Drinks (UQ Staff Club)
18:30
CityCat from UQ to Southbank for dinner
WEDNESDAY, February 2
PAGANZ (III) Room 309, Steele Building, School of Pharmacy
09:00 – 10:30
Prof Mats Karlsson, Department of Pharmacy, University of Uppsala, Sweden
Estimation of Optimal Dose Individualization Strategies
Dr Diane Mould, SmithKlineBeecham, Pennsylvania, USA
A Population Pharmacokinetic and Pharmacodynamic Analysis of Drug “X”
10:30 – 11:00
Morning tea
11:00 – 13:00
Assoc Prof Nick Holford, Department of Pharmacology & Clinical Pharmacology, University of Auckland, Auckland, NZ
Overview of the WinNONMIX program
Dr Noel Cranswick, Clinical Pharmacology, Royal Children’s Hospital, Melbourne
Using WinNONMIX to Model Paediatric Pharmacokinetic Data – A Layperson’s Approach
Dr Diane Mould, SmithKlineBeecham, Pennsylvania, USA
Assessing Pharmacokinetic and Pharmacodynamic Drug Interactions with Drug “X”
13:00 – 14:00
Lunch (UQ Staff Club)
14:00 – 15:30
Assoc Prof Nick Holford, Department of Pharmacology & Clinical Pharmacology, University of Auckland, Auckland, NZ
Three Stage Model Evaluation – A Form of Posterior Predictive Check
Mr John Parke, Chief Pharmacist, QEII Hospital, Brisbane
Role of the Bootstrap Approach in Evaluating Population Models
15:30
General discussion, closing remarks
Afternoon tea, farewells
ACCOMMODATION
There is a large variety of accommodation in Brisbane City or in the immediate surrounds, including many modern hotels of international standard (e.g. Hilton, Sheraton, Marriott). Those listed below are included only to indicate the range available. Delegates should make their own arrangements for travel, transfers and accommodation. The rates and conditions quoted below should be confirmed with the hotel beforehand. To qualify for any university/hospital/government rate delegates should bring a business card, employee declaration, pay advice, etc.
Rydges Brisbane Southbank
Glenelg Street
South Brisbane QLD 4101
+61 7 3255 0822 (Tel)
+61 7 3255 0899 (Fax)
A new, high quality hotel located in the Southbank area, and adjacent to the Performing Arts complex, museums, eateries. A pleasant 10 min walk across Victoria Bridge into the City. Special university conference rate: $120 – $140 double/twin
The Heritage Hotel
39 Edward Street
Brisbane, QLD 4000
+61 7 3221 1999 (Tel)
+61 7 3221 6895 (Fax)
This is one of the best hotels in Brisbane situated in the City on the Brisbane River adjacent to the Botanic Gardens. Where the celebrities stay when in town! Special rate for universities, government departments, hospitals: $165 double/twin
Normal rate: $230 double/twin
Qantas Frequent Flyer rate: $200 double/twin
Inn on the Park
507 Coronation Drive
Toowong, QLD 4066
+61 7 3870 9222 (Tel)
+61 7 3870 2246 (Fax)
A smaller establishment with a unique colonial appeal on the Brisbane River halfway between the City and the University of Queensland (approx 4 km away).
$95 single/twin/double (>2 nights stay attracts a welcome dinner to the value of $30).
Coronation Motel
205 Coronation Drive
Milton QLD 4064
+61 7 3369 9955 (Tel)
+61 7 3369 5066 (Fax)
Situated on the main route between the City and University of Queensland.
$79 single/double/twin
The Women’s College
College Road
The University of Queensland, QLD 4072
+61 7 3377 4500 (Tel)
+61 7 3870 9511 (Fax)
A major residential college located on campus a few minute’s walk from the centre of the University via the river, lakes and parklands. It offers single rooms with shared facilities at $50 per night, including cooked breakfast.
REGISTRATION
PAWS + PAGANZ $175
PAGANZ $100
Registration deadline is Monday, January 24, 2000.
The registration fee covers attendance, morning and afternoon refreshments (coffee/tea/juice/mineral water), lunches and honorary membership at the University of Queensland Staff Club (31st January – 2nd February, inclusive), conference dinner including CityCat (high-speed catamaran) transport down river from the University of Queensland to Southbank. Cost of an accompanying person for the dinner is $40.
Payment should be in Australian dollars by cheque, or by an international bank draft drawn on an Australian bank (e.g. Commonwealth Bank) for overseas delegates. Make all cheques payable to: THE UNIVERSITY of QUEENSLAND
A receipt of payment will be issued at the meeting.
As advised previously, the number of computer workstations available for the PAWS section of the meeting is limited, therefore, places will be allocated on a first-come basis. Registration will be confirmed only on receipt of payment (Sorry, we cannot handle credit card transactions or EFT for this meeting).
There is no restriction on numbers for the PAGANZ section of the meeting.
To register for PAWS-PAGANZ 2000 complete the Attached registration form and mail with payment to:
BG Charles
(PAWS-PAGANZ 2000)
School of Pharmacy
The University of Queensland
QLD 4072 Australia
PRESENTATIONS
You are encouraged to present planned, in-progress, or completed population studies (15:30-17:30, Tuesday, February 1st) in an informal environment. These will be of 10-15 minutes duration with 5-10 minutes for discussion/questions depending on the final number of submissions. There will be computer presentation facilities, 35 mm slide projector, overhead projector, and whiteboards available. Those intending to present should submit an abstract of no more than 1 page, with title, authors(s) and institution(s) and send this to me as an email Attachment.
MEETING LOCATION
The meeting is being held at The University of Queensland, Brisbane, St Lucia campus. The PAGANZ section will be held in the School of Pharmacy, Room 309, Steele Building (building No. 3 on the University map which is displayed throughout the campus). Attendees should report here by 08:30 on Monday, January 31. The PAWS sessions will be conducted in the PC laboratory on the ground floor of the Biological Sciences Library (building No. 94). Lunches and drinks will be in the Staff & Graduates Club, Staff House (building No. 41).
CONTACT
All queries for PAWS-PAGANZ 2000 should be directed to:
Bruce CHARLES, PhD
University of Queensland, School of Pharmacy, QLD 4072
Australia
+61 7 336 53194 (TEL)
+61 7 336 51688 (FAX)