PAGANZ Program

Program for PAGANZ presentations (Thursday 29th–Friday 30th)

Thursday (29th) ISOP Lecture – Carl Kirkpatrick (Chair) Speaker
1330-1335 Welcome Carl Kirkpatrick
1335-1430 ISOP Lecture – A hitchhikers guide to model selection Rob Bies
1430-1500 Afternoon Tea
  Free Oral Presentations- Bruce Green (Chair)  
1500-1515 Application of relative forgiveness using clinically observed adherence profiles Piyanan Assawasuwannakit
1515-1530 Model-based estimation of anticholinergic burden Mohammed Salahudeed
1530-1545 Busulfan Target Concentration Intervention Audit and Model Evaluation Nick Holford
1545-1600 Allopurinol dosing in patients with renal impairment Dan Wright
1600-1615 A population PKPD model for neutropenia during Hyper-CVAD chemotherapy in non-Hodgkin lymphoma Geeta Sandhu
1615-1630 Impact of high-flux haemodialysis on the probability of target attainment for amoxycillin/clavulanic acid combination therapy Katrina Hui
1630-1730 Annual General Meeting – Cossar Hall  All participants
 1800 Conference Dinner  All Participants


Friday (30th)    
0800-0830 Registration and Coffee
  Free Oral presentations- Stephen Duffull (Chair)  
0830-0845 A systems pharmacology model for pharmacokinetic disposition of a ketone monoester and its metabolism products in human Vittal Shivva
0845-0900 Characterising the transmission dynamics of Acinetobacter baumannii in intensive care units using hidden Markov models Tan Doan
0900-0915 Time-to-event model of leflunomide cessation due to toxicity in rheumatoid arthritis patients: Genetic polymorphism of CYP1A2 but not total or free teriflunomide concentrations is associated with cessation Ashley Hopkins
0915-0930 A Systematic Evaluation of Single Metrics in Discriminating Changes in Rheumatoid Arthritis Disease Activity Jessica Wojciechowski
0930-0945 A repeated time-to-event analysis of onset and offset times of sildenafil erectile response Hankil Son
0945-1000 The hazards of acquiring Aspergillus positive culture in children with cystic fibrosis Sabariah Noor Harun
1000-1030 Morning tea
  Focus on Monash- Nick Holford (Chair)  
1030-1050 Modelling the antiviral effect of oseltamivir against influenza kinetics, immune response and symptom dynamics Kashyap Patel
1050-1110 Population modelling of lithium in paediatric patients with bipolar disorder: implications for dosing Cornelia Landersdorfer
1110-1130 A Novel Interdisciplinary Pharmacometric Approach: Linking Oseltamivir PK/PD to Dynamic Transmission and Health Economic Models to Inform Antiviral Use in Pandemic Scenarios Carl Kirkpatrick
  Free Oral Presentations – Nick Holford (chair)   
1130-1145 Automated proper lumping for the simplification of linear systems Shan Pan
1145-1200 Redefining normal variability of drug disposition Hesh Al-Sallami
1200-1215 A suggestion for determining systematic bias when measuring predictive performance Shamin Saffian
1215-1230 The effects of polypharmacy and Drug Burden Index on transitions in cognitive function and death: the CHAMP study   Kris Jamsen


1230-1330 Lunch
  Free Oral Presentations  –  Kashyap Patel (Chair)  
1330-1345 Population pharmacokinetic modelling of itraconazole and hydroxyl-itraconazole for oral Lozanoc® and Sporanox® capsule formulations in healthy volunteers in fed and fasted state. Ahmad Abuhelwa
1345-1400 Mechanism-based pharmacodynamic modelling approach to optimise synergistic carbapenem plus aminoglycosides combinations to combat carbapenem-resistant Acinetobacter baumannii Rajbharan Yadav
1400-1415 Modeling of blood pressure lowering effect for co-administration of valsartan and amlodipine Young-A Heo
1415-1430 Quantitative Assessment of Nocturia Patient’s Urination Pattern and Drug Treatment Effects using a Joint Ordered Categorical Model Hyerang Roh
1430-1445 Pharmacokinetic modelling of enterohepatic circulation of mycophenolic acid in Malaysian lupus nephritis patients Nurul Azrin Abd Rahman
1445-1500 TBC TBC
1500 Afternoon tea, Presentation of the Nick Holford student prize, close of meeting Carl Kirkpatrick (Chair)