Dose optimization of linezolid among surgical patients in Pakistan: A population pharmacokinetic study

Background Linezolid belongs to oxazolidinone class of antibiotics and is primarily used for the treatment of sever infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant Enterococcus (VRE). It inhibits bacterial protein synthesis by blocking the formation of initiation complex in ribosomes. Linezolid is eliminated through both renal and hepatic routes. It is classified […]