Bayesian Forecasting of Ribavirin in Hepatitis C patients: Population model and validation.

Background: Dual therapy of ribavirin and pegalated interferon is the first line therapy for Hepatitis C. Ribavirin has a narrow therapeutic index with high plasma concentrations resulting in haemolytic anaemia. The aim of ribavirin therapy is to reduce serum viral load whilst minimizing side effects. Strategies such as dosing on body weight or according to […]