January 15, 2019
Authors Xiaoyan YANG (1,2),Nick HOLFORD (2),Zhimei JIANG (3),Hongxin SHEN (3),Jing SHI (1)*,Xianxiao SHU (1),Yi HUANG (1),Jing ZHAO (1),Jun TANG (1),Dezhi MU (1)
Affiliations 1. Department of Pediatrics, West China Second University Hospital, Sichuan University Chengdu 610041, China; 2. Dept Pharmacology & Clinical Pharmacology, University of Auckland, Auckland 1010, New Zealand; 3. Department of Pharmacology, West China Second University Hospital, Sichuan University Chengdu 610041, China
Presentation type Oral
Presenters Xiaoyan YANG,Nick HOLFORD
Objective: Apnea of prematurity (AOP) is defined as an attack of apnea for at least 20 seconds, with bradycardia and cyanosis. It is a common phenomenon in the neonatal intensive care unit (NICU). Caffeine citrate, one of the methylxanthines, is used to suppress or to prevent AOP attack. This study aimed to develop a population pharmacokinetic (popPK) […]