Introduction Upper urinary tract infections (UTI) are associated with critical illness and significant mortality. Meropenem is efficacious in treating UTI and has a systemic and urinary minimum inhibitory concentrations (MIC) breakpoint of 1 mg/L for Enterobacterales and 2 mg/L for Pseudomonas aeruginosa. As the fraction of meropenem excreted in the urine decreases with declining renal function, we applied […]
