Patient-reported outcomes predict survival and adverse events following anticancer medicines initiation

Background The prognostic value of patient-reported outcomes (PROs) has been minimally explored in advanced breast cancer, and their comparative prognostic performance against Eastern Cooperative Oncology Group performance status (ECOG PS) is largely unknown. Methods This study pooled individual participant data from clinical trials CLEOPATRA, EMILIA, and MARIANNE. Pre-treatment PRO associations with overall survival (OS), progression-free […]