Introduction: Tacrolimus (TAC) is a cornerstone immunosuppressant in liver transplantation, characterized by a narrow therapeutic index and substantial pharmacokinetic variability, making dose optimization challenging. Objective: This study aimed to develop a population pharmacokinetic (PopPK) model for TAC in Vietnamese liver transplant patients, integrating CYP3A5 genetic polymorphisms to support individualized dosing. Methods: Data from 95 Vietnamese liver […]
