Population pharmacokinetic and pharmacodynamics analysis of lipid emulsion propofol in pediatric patients

Aim: This study aimed to characterize the pharmacokinetics and pharmacodynamics of lipid emulsion propofol administered by a target-controlled infusion (TCI) anesthesia in pediatric surgery. Method: Forty patients (ASA PS 1,2) aged 2–12 years were given an intravenous bolus of 2% propofol (Fresofol?, Fresenius Kabi Korea Ltd., Korea) 3 mg/kg, followed by continuous infusion at the rate of 200 mg/kg/min for […]