kieraharwood

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Pharmacokinetics of tobramycin in children with cystic fibrosis

Introduction: Cystic fibrosis (CF) is a genetic condition characterised by severe lung disease often requiring frequent hospital admissions for pulmonary exacerbations requiring intravenous antibiotic treatment. Tobramycin, an aminoglycoside antibiotic, is commonly used to treat pulmonary exacerbations in those with Pseudomonas aeruginosa infections; however, it is unknown whether current paediatric dosing regimens achieve safe and effective […]

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