Introduction: Primaquine is the only widely available drug that targets Plasmodium vivax malaria parasites in the liver. However, primaquine is underused because of concerns that this drug can cause dose-dependent haemolysis in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals. We developed and calibrated a within-host Bayesian pharmacodynamic model of red blood cell (RBC) production and turnover to […]
