Population Pharmacokinetics of Paracetamol in Overdose in a Single Patient

Background: A lack of substantial pharmacokinetic analysis in overdose exists, because of uncertainty in dose and time of ingestion, and limited sampling in the absorption phase. Population pharmacokinetic analyses with uncertainty models have been used in overdose to understand dose-concentration relationships. This study uses concentration-time data in a single patient with multiple occasions of paracetamol […]