• University of Auckland

Author Archive | Jeffery

Parameter Analysis for PBPK Model for Enalapril

Physiologically based pharmacokinetic (PBPK) modeling is valuable for drug development (Phase I). While PBPK models may share similar compartmental structures (e.g., blood, liver) for different species, a distinct set of physiological (e.g. compartmental volume and blood flow rate) and drug-specific (e.g. metabolism and clearance rates) parameters need to be used in different species. However, it […]

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