December 5, 2019
Authors Ranita Kirubakaran (1,2), Stefanie Hennig (3,4), Ben Maslen (5), Jane E Carland (1,2), Richard O Day (1,2), Sophie L Stocker (1,2)
Affiliations 1. St Vincent's Clinical School, UNSW, Sydney, 2. Dept of Clin Pharmacol and Toxicol, St Vincent's Hosp, Sydney, 3. School of Pharmacy, UQ, Brisbane, 4. Certara, Inc., Princeton, 5. Mark Wainwright Analytical Centre, UNSW, Sydney.
Presentation type Oral
Presenters Ranita Kirubakaran
Background. Numerous population pharmacokinetic (popPK) models of tacrolimus (TAC) in adult transplant recipients have been published. However, data on the accuracy of Bayesian forecasting with concomitant azole therapy or extrapolation to other transplant cohorts are scarce. Aims. To externally validate the predictive performances of relevant popPK models of TAC in adult heart transplant (HTX) recipients […]