Lean body weight versus total body weight for propofol dosing

Background: Clinicians have observed longer awakening times for obese compared to normal-weight patients when propofol is dosed as per label guidelines on Total Body Weight (TBW).  This may be explained by the non-linear relationship between TBW and CL described by Schuttler et al1.  Lean Body Weight (LBW) has been reported to have a linear relationship with […]