Objective: The objective of this presentation was to demonstrate a new method to identify continuous covariates. The investigation of time after kidney transplant as a covariate on tacrolimus bioavailability was used as an example. Methods: A total of 3100 tacrolimus concentration-time points were obtained from 242 patients who underwent kidney transplantation at Oslo University Hospital […]
Identification of continuous covariate relationships
February 4, 2013
Authors Elisabet Størset (1), Christine Staatz (2), Stefanie Hennig (2), Troels. K Bergmann (3), Nick Holford (4)
Affiliations 1. School of Pharmacy, University of Oslo, Norway, 2. School of Pharmacy, University of Queensland, Brisbane; Australian Centre of Pharmacometrics 3. Department of Pharmacology, Aarhus University, Aarhus, Denmark 4. Department of Pharmacology and Clinical Pharmacology, University of Auckland, New Zealand
Presentation type Oral
Presenters Elisabet Størset