Introduction Mycophenolic acid (MPA) is an immunosuppressant agent which is increasingly be used in treatment of lupus nephritis patients. Currently it is given as a fixed dose without drug concentration monitoring, however it is likely patients would benefit from more individualised treatment. The objective of this current study is to develop a population pharmacokinetic model […]
Azrin Abd Rahman
- University of Queensland
Author Archive | Azrin Abd Rahman
A Review of Population Pharmacokinetic and Pharmacodynamic Studies of Mycophenolate in Autoimmune Disease Patients
January 30, 2013
Authors Nurul Azrin Abd Rahman (1,2), Susan Tett (1), Christine Staatz (1)
Affiliations 1. University of Queensland, 2. International Islamic University of Malaysia
Presentation type Poster
Presenters Nurul Azrin Abd Rahman
Introduction: Mycophenolic acid (MPA), the active drug moiety of mycophenolate, is a potent immunosuppressant agent, which is increasingly being used in the treatment of patients with various autoimmune diseases. Despite the accumulation of promising clinical data on the benefits of mycophenolate in autoimmune diseases, there is a relative lack of data on its pharmacokinetics and […]